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  • The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence according to a news release by them on 10-12-2010.

    Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err on the side of caution and permit the FDA do its job and demand some research be done in order that the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say everything to keep people on the medications.

    Researchers discovered that participants using this drug for any year, lost weight within one month and have kept the extra weight off during the entire 56 weeks of the study. Contrave can be a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which can be made up of more than one active ingredient, that might make them far better and safer.

    Combo-pilling may be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular may be the fact that as of right now there are not any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise blood pressure levels and pulse rate, and shouldn't be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not used in patients with uncontrolled high hypertension, as well as by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.

    Suboxone is made up of two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but when the tablet is dissolved in water and injected the naloxone will cause instant withdrawal. When suboxone can be used correctly, the naloxone is destroyed inside the liver shortly after uptake in the intestines and it has no therapeutic effect. Buprenorphine is the active substance; it's absorbed within the tongue (and through the mouth) but destroyed by the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I used this formulation once the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have treated addicts who've had gastric bypass, where the first part of the intestine is bypassed along with the stomach contents empty right into a more distal part of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy in which the drug is taken up with the duodenum and transferred directly to the liver from the portal vein, where it really is quickly and completely destroyed. After gastric bypass naloxone can be adopted by areas of the intestine which aren't served with the portal system, causing blood amounts of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.