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  • On September 26, UCLA researcher reported the final results of a study, which indicated that Asians who are struggling with alcoholism may benefit especially from naltrexone, among three medications authorized by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation that makes them planning to benefit from naltrexone, compared with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are presently available online ( inside journal Neuropsychopharmacology and will also be published in an upcoming print edition from the journal.

    Using two separate drugs to lose weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you ought to err on the side of caution and allow FDA do its job and demand some research be done so your public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to earn money and that they would say everything to keep people on his or her medications.

    Researchers found that participants taking this drug for any year, dropped a few pounds within a month and have kept the body weight off through the 56 weeks in the study. Contrave is really a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs that are made up of many active ingredient, that might make them more efficient and safer.

    Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills has become popular will be the fact that since right now there are no long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug also can raise hypertension and pulse rate, and shouldn't be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    "There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.